There are 3 currently available in the US including Botox, Xeomin and Jeuveau. All 3 products work in a very similar fashion.

The most common use of these neuromodulators is for correcting creases in the skin caused by repeated muscle movement. Repeated muscle movement creases the skin in much the same way that your letter of becomes creased. The difference is that since your skin is a living organ, if you correct for the cause of the creases, the creases will improve or go away. It is important to understand that these treatments do not fix wrinkles. The most common areas to treat these creases are the forehead lines, frown lines and crow’s feet around the eyes.

It is this same mechanism of relaxing muscles that has led to neuromodulators being used for the treatment of certain headaches such as migraines. In addition, it has an effect on certain nerve endings which makes it very effective is for treating hyperhidrosis [increased sweating].

I have been injecting neuromodulators in Seattle for 20 years and was injecting in Canada before then. I feel it’s important to have a board-certified dermatologist do the injections and preferably one who has an interest in cosmetic dermatology.

Peter Jenkin, MD, FAAD, FRCPC
Board-Certified Dermatologist
Dermatology Associates of Seattle

Peter Jenkin, Clinic Director and Board-Certified Dermatologist at Dermatology Associates of Seattle is available for consultation. For scheduling and information, visit us at